QueStions AND


What is Barrigel made of and is it safe?

Barrigel is the first and only hyaluronic acid prostate spacer on the market. Barrigel is made from Non-Animal Stabilised Hyaluronic Acid, known as NASHA®. NASHA has a long history of safety, efficacy, and biocompatibility in a wide variety of medical applications, including paediatric medicine.1,2 It is a well-known technology in aesthetic markets as a dermal filler, and has been used in over 40-million treatments globally across all approved indications.3

What are the risks associated with Barrigel?

As with any injection procedure, there is a risk of infection. Potential procedure-related side effects can include pain at the injection site and a brief period of bleeding from the needle stick. Post-treatment side effects include mild to moderate sensation of rectal filling. Talk to your doctor about the risks associated with Barrigel.

How is Barrigel implanted?

Barrigel is implanted through a needle. Your physician will use imaging technology during the procedure to sculpt the Barrigel implant to your anatomy.

Where is the procedure done?

Barrigel can be implanted in a hospital prior to the start of radiation treatment. The implant is typically inserted at the same time as fiducial marker placement.

How long before I can get back to regular activities following the procedure?

Your physician is the best person to consult for timing on returning to your regular activities.

How long will Barrigel remain in my body?

Barrigel is a hyaluronic acid spacer that is biocompatible with your body. The implant will stay in place for the duration of your radiation therapy and begin to safely reabsorb into your body after 9 months.4 It is important to note that the implant may be detected during anorectal examinations and medical imaging of the pelvis. It is important to inform your future physicians that you have had treatment with Barrigel.

Which types of radiation therapy can Barrigel be used with?

Barrigel can be used with all forms of radiation therapy available for treating prostate cancer patients with clinical stage T1-T3.5 Talk with your doctor to find out if Barrigel is right for you.


To learn more please click below for resources PDFs.

BARRIGEL patient brochure
BARRIGEL Instructions for Use

If you are a healthcare professional and would like to receive more information about Barrigel please contact

References: 1. Q-Med. NASHA- the Monograph. Uppsala, Sweden.  2. Cerwinka WH, Scherz HC, Kirsch AJ. Endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children. Advances in Urology. 2008; 1-7.  3. Galderma. Restylane. Available at: Accessed September 1, 2020.  4. Mok G, Benz E, Vallee JP, et al. Optimization of radiation therapy techniques for prostate cancer with prostate-rectum spacers: A systematic review. Int J Radiat Oncol Biol Phys. 2014;90(2):278-288.  5. Barrigel [product insert – Europe] Santa Barbara, CA, United States. Palette Life Sciences; 2021.